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Cellosaurus SNU-1544 (CVCL_5027)

[Text version]
Cell line name SNU-1544
Synonyms SNU1544
Accession CVCL_5027
Resource Identification Initiative To cite this cell line use: SNU-1544 (RRID:CVCL_5027)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 42 hours (PubMed=20176655).
Microsatellite instability: Instable (MSI-high) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Unspecified (PubMed=20176655).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
  • Mutation; HGNC; 7127; MLH1; Simple; p.Ser2Leu (c.5C>T); ClinVar=VCV000182533; Zygosity=Unspecified (PubMed=20176655).
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001786; KCLB=01544; PubMed=20176655; PubMed=25926053

Markers:
AmelogeninX
CSF1PO11,12 (KCLB=01544; PubMed=20176655; PubMed=25926053)
11.1,12 (DepMap=ACH-001786)
D2S133819
D3S135815,16
D5S81812
D7S82011,12
D8S117910
D13S3179,11
D16S5398,14
D18S5112,17
D19S43314.2,16.2
D21S1129,30
FGA20,23,24 (DepMap=ACH-001786)
20,24 (PubMed=20176655)
Penta D8,12
Penta E9,16
TH017,9
TPOX8
vWA14,19,20,21 (DepMap=ACH-001786)
14,20 (KCLB=01544; PubMed=20176655)
14,20,21 (PubMed=25926053)

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Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) KCLB; 01544
Cell line databases/resources cancercelllines; CVCL_5027
Cell_Model_Passport; SIDM01838
ColonAtlas; SNU1544
DepMap; ACH-001786
Encyclopedic resources Wikidata; Q54955119
Gene expression databases GEO; GSM1448192
Polymorphism and mutation databases Cosmic; 1322292
IARC_TP53; 28480
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number24