Cell line name |
SNU-1544 |
Synonyms |
SNU1544 |
Accession |
CVCL_5027 |
Resource Identification Initiative |
To cite this cell line use: SNU-1544 (RRID:CVCL_5027) |
Comments |
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: Seoul National University (SNU) cell line collection. Population: Korean. Doubling time: 42 hours (PubMed=20176655). Microsatellite instability: Instable (MSI-high) (PubMed=20176655; PubMed=25926053). Omics: Transcriptome analysis by microarray. Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156. |
Sequence variations |
- Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Unspecified (PubMed=20176655).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
- Mutation; HGNC; 7127; MLH1; Simple; p.Ser2Leu (c.5C>T); ClinVar=VCV000182533; Zygosity=Unspecified (PubMed=20176655).
- Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Female |
Age at sampling |
38Y |
Category |
Cancer cell line |
STR profile |
Source(s): DepMap=ACH-001786; KCLB=01544; PubMed=20176655; PubMed=25926053
Markers:Amelogenin | X |
CSF1PO | 11,12 (KCLB=01544; PubMed=20176655; PubMed=25926053) 11.1,12 (DepMap=ACH-001786) |
D2S1338 | 19 |
D3S1358 | 15,16 |
D5S818 | 12 |
D7S820 | 11,12 |
D8S1179 | 10 |
D13S317 | 9,11 |
D16S539 | 8,14 |
D18S51 | 12,17 |
D19S433 | 14.2,16.2 |
D21S11 | 29,30 |
FGA | 20,23,24 (DepMap=ACH-001786) 20,24 (PubMed=20176655) |
Penta D | 8,12 |
Penta E | 9,16 |
TH01 | 7,9 |
TPOX | 8 |
vWA | 14,19,20,21 (DepMap=ACH-001786) 14,20 (KCLB=01544; PubMed=20176655) 14,20,21 (PubMed=25926053) |
Run an STR similarity search on this cell line |
Publications | PubMed=20176655; DOI=10.1093/carcin/bgq043 Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G. Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. Carcinogenesis 31:1003-1009(2010) PubMed=25926053; DOI=10.1038/ncomms8002 Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A. The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets. Nat. Commun. 6:7002.1-7002.10(2015) |
Cross-references |
Cell line collections (Providers) |
KCLB; 01544
|
Cell line databases/resources |
cancercelllines; CVCL_5027
Cell_Model_Passport; SIDM01838
ColonAtlas; SNU1544
DepMap; ACH-001786
|
Encyclopedic resources |
Wikidata; Q54955119
|
Gene expression databases |
GEO; GSM1448192
|
Polymorphism and mutation databases |
Cosmic; 1322292
IARC_TP53; 28480
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 02-May-2024 |
Version number | 24 |
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