Cellosaurus cell line SNU-1411 (CVCL

Cellosaurus SNU-1411 (CVCL_5025)

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Cell line name

SNU-1411

Synonyms

SNU1411

Accession

CVCL_5025

Resource Identification Initiative

To cite this cell line use: SNU-1411 (RRID:CVCL_5025)

Comments

Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 38 hours (PubMed=20176655).
Microsatellite instability: Stable (MSS) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Rectum; UBERON=UBERON_0001052.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (PubMed=20176655).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser94Ter (c.281C>A); Zygosity=Homozygous (PubMed=20176655).

Disease

Rectal adenocarcinoma (NCIt: C9383)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

42Y

Category

Cancer cell line

STR profile

Source(s): KCLB=01411; PubMed=20176655; PubMed=25926053; Technion Genomics Center

Markers:

Amelogenin	X
CSF1PO	10,12
D1S1656	16,17.3
D2S441	10,11
D2S1338	19,24
D3S1358	15
D5S818	11,13
D7S820	11
D8S1179	15 (PubMed=20176655) 15,16 (Technion Genomics Center)
D10S1248	13
D12S391	19
D13S317	10 (PubMed=25926053) 10,11 (KCLB=01411; PubMed=20176655; Technion Genomics Center)
D16S539	12,13
D18S51	14
D19S433	14
D21S11	30
D22S1045	16,17
FGA	23,24
Penta D	5,12
Penta E	16,18
TH01	9
TPOX	8
vWA	20

Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ja-Lok Ku, Young-Kyoung Shin, Duck-Woo Kim, Kyung-Hee Kim, Jin-Sung Choi, Sung-Hye Hong, You-Kyung Jeon, Sung-Hee Kim, Hong-Sun Kim, Jae-Hyun Park, Il-Jin Kim, Jae-Gahb Park;
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references

Cell line collections (Providers)

KCLB; 01411

Cell line databases/resources

cancercelllines; CVCL_5025
ColonAtlas; SNU1411

Encyclopedic resources

Wikidata; Q54955115

Gene expression databases

GEO; GSM1448157

Polymorphism and mutation databases

Cosmic; 1322290
IARC_TP53; 28477

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number