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Cellosaurus SNU-1077 (CVCL_5007)

[Text version]
Cell line name SNU-1077
Synonyms SNU1077
Accession CVCL_5007
Resource Identification Initiative To cite this cell line use: SNU-1077 (RRID:CVCL_5007)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 43 hours (PubMed=9299262).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Ile195Ser (c.584T>G); ClinVar=VCV000376619; Zygosity=Homozygous (DepMap).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:06,24:02
HLA-BB*40:06,67:01
HLA-CC*07:02,08:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.64
Native American0
East Asian, North64.52
East Asian, South33.3
South Asian0
European, North0
European, South1.53
Disease Uterine carcinosarcoma (NCIt: C42700)
Carcinosarcoma of the corpus uteri (ORDO: Orphanet_213610)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
D3S135815,16
D5S81811,13
D7S8208
D13S31712
FGA24,25
TH017,9
TPOX8
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=9299262; DOI=10.1006/gyno.1997.4802
Yuan Y., Kim W.-H., Han H.S., Lee J.-H., Park H.-S., Chung J.-K., Kang S.-B., Park J.-G.
Establishment and characterization of cell lines derived from uterine malignant mixed Mullerian tumor.
Gynecol. Oncol. 66:464-474(1997)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 01077
Cell line databases/resources cancercelllines; CVCL_5007
Cell_Model_Passport; SIDM00166
DepMap; ACH-000302
Biological sample resources BioSample; SAMN10987741
Chemistry resources PharmacoDB; SNU1077_1438_2019
Encyclopedic resources Wikidata; Q54955095
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887604
GEO; GSM888687
Polymorphism and mutation databases IARC_TP53; 28344
LiGeA; CCLE_902
Progenetix; CVCL_5007
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23