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Cellosaurus SNU-1066 (CVCL_5005)

[Text version]
Cell line name SNU-1066
Synonyms SNU1066
Accession CVCL_5005
Resource Identification Initiative To cite this cell line use: SNU-1066 (RRID:CVCL_5005)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 48 hours (PubMed=10369293).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp92fs*54 (c.274delG); Zygosity=Homozygous (PubMed=10369293; DepMap=ACH-000682).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.514_559del46; Zygosity=Homozygous (PubMed=10369293; DepMap=ACH-000682).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:06,24:02
HLA-BB*15:01,27:05
HLA-CC*01:02,04:01
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): KCLB=01066

Markers:
AmelogeninX,Y
CSF1PO11
D3S135817
D5S8189,11
D7S82012
D13S3178,12
FGA23
TH017,9
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=10369293; DOI=10.1097/00005537-199906000-00025
Ja-Lok Ku, Woo-Ho Kim, Jae-Ho Lee, Hyun-Sook Park, Kwang Hyun Kim, Myung-Whun Sung, Jae-Gahb Park;
Establishment and characterization of human laryngeal squamous cell carcinoma cell lines.
Laryngoscope 109:976-982(1999)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ja-Lok Ku, Jae-Gahb Park;
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 01066
Cell line databases/resources Cell_Model_Passport; SIDM00170
DepMap; ACH-000682
Anatomy/cell type resources BTO; BTO_0005924
Biological sample resources BioSample; SAMN10987965
Chemistry resources PharmacoDB; SNU1066_1436_2019
Encyclopedic resources Wikidata; Q54955092
Gene expression databases ArrayExpress; E-MTAB-2770
Polymorphism and mutation databases Cosmic; 934176
IARC_TP53; 11324
LiGeA; CCLE_560
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26