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Cellosaurus AM-1 (CVCL_4Z40)

[Text version]
Cell line name AM-1
Accession CVCL_4Z40
Resource Identification Initiative To cite this cell line use: AM-1 (RRID:CVCL_4Z40)
Comments Population: Japanese.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Bone, jaw, mandible; UBERON=UBERON_0001684.
Cell type: Ameloblast; CL=CL_0000059.
Disease Plexiform ameloblastoma (NCIt: C39753)
Ameloblastoma (ORDO: Orphanet_314419)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 20Y
Category Transformed cell line
Publications

PubMed=9682983; DOI=10.1111/j.1600-0714.1998.tb01943.x
Hidemitsu Harada, Takeshi Mitsuyasu, Norifumi Nakamura, Yuichiro Higuchi, Kuniaki Toyoshima, Akiyoshi Taniguchi, Shigeru Yasumoto;
Establishment of ameloblastoma cell line, AM-1.
J. Oral Pathol. Med. 27:207-212(1998)

PubMed=23706918; DOI=10.1016/j.oooo.2013.03.005
Toshiro Kibe, Takao Fuchigami, Michiko Kishida, Mikio Iijima, Kiyohide Ishihata, Hiroshi Hijioka, Akihiko Miyawaki, Ichiro Semba, Norifumi Nakamura, Tohru Kiyono, Shosei Kishida;
A novel ameloblastoma cell line (AM-3) secretes MMP-9 in response to Wnt-3a and induces osteoclastogenesis.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 115:780-788(2013)

PubMed=32348439; DOI=10.1590/1678-7757-2019-0558; PMCID=PMC7185982
Takao Fuchigami, Hajime Suzuki, Takuya Yoshimura, Toshiro Kibe, Elissa Chairani, Tohru Kiyono, Michiko Kishida, Shosei Kishida, Norifumi Nakamura;
Ameloblastoma cell lines derived from different subtypes demonstrate distinct developmental patterns in a novel animal experimental model.
J. Appl. Oral Sci. 28:e20190558.1-e20190558.7(2020)

PubMed=36452176; DOI=10.1016/j.mbplus.2022.100125; PMCID=PMC9703037
Deniz Bakkalci, Amir Zaki Abdullah Zubir, Syed Ali Khurram, Judith Pape, Kristiina Heikinheimo, Stefano Fedele, Umber Cheema;
Modelling stromal compartments to recapitulate the ameloblastoma tumour microenvironment.
Matrix Biol. Plus 16:100125.1-100125.13(2022)

Cross-references
Encyclopedic resources Wikidata; Q54749549
Polymorphism and mutation databases Cosmic; 2163016
Cosmic; 2209114
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number15