| Cell line name |
TC-244 |
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| Accession |
CVCL_4Z34 |
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| Resource Identification Initiative |
To cite this cell line use: TC-244 (RRID:CVCL_4Z34) |
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| Comments |
Omics: Transcriptomics; RNAseq. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=25010205).
- Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=25010205).
|
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| Disease |
Ewing sarcoma/peripheral primitive neuroectodermal tumor (NCIt: C27291)
Bone sarcoma (ORDO: Orphanet_223727) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): PubMed=25010205
Markers:| Amelogenin | X,Y |
| CSF1PO | 11 |
| D2S1338 | 23,25 |
| D3S1358 | 16,17 |
| D5S818 | 11,12 |
| D7S820 | 9,11 |
| D8S1179 | 14,16 |
| D13S317 | 11 |
| D16S539 | 9,10 |
| D18S51 | 12,14 |
| D19S433 | 15 |
| D21S11 | 29,30 |
| FGA | 21,27 |
| TH01 | 8,9 |
| TPOX | 11 |
| vWA | 18,19 |
Run an STR similarity search on this cell line |
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| Publications | PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782
Andrew S. Brohl, David A. Solomon, Wendy Chang, Jian-Jun Wang, Young Song, Sivasish Sindiri, Rajesh Patidar, Laura Hurd, Li Chen, Jack F. Shern, Hong-Ling Liao ...Show all 26 authors... , Xin-Yu Wen, Julia Gerard, Jung-Sik Kim, Jose Antonio Lopez-Guerrero, Isidro Machado, Daniel H. Wai, Piero Picci, Timothy J. Triche, Andrew E. Horvai, Markku Martti Miettinen, Jun S. Wei, Daniel Catchpoole, Antonio Llombart-Bosch, Todd A. Waldman, Javed Khan; Show fewer authors
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:e1004475.1-e1004475.13(2014) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54971803
|
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| Polymorphism and mutation databases |
Cosmic; 2228240
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| Entry history |
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| Entry creation | 14-Dec-2015 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 10 |
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