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Cellosaurus OV90D-6 (CVCL_4Z25)

[Text version]
Cell line name OV90D-6
Accession CVCL_4Z25
Resource Identification Initiative To cite this cell line use: OV90D-6 (RRID:CVCL_4Z25)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene fusion; HGNC; 1790; CDKN2D + HGNC; 20482; WDFY2; Name(s)=CDKN2D-WDFY2 (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Arg445Ter (c.1333C>T); ClinVar=VCV000024850; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser215Arg (c.643A>C); ClinVar=VCV000428895; Zygosity=Homozygous (from parent cell line).
Disease Ovarian adenocarcinoma (NCIt: C7700)
Adenocarcinoma of ovary (ORDO: Orphanet_213504)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3768 (OV-90)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=22141344; DOI=10.1186/1757-2215-4-21
Sherman-Baust C.A., Becker K.G., Wood W.H. III, Zhang Y.-Q., Morin P.J.
Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin.
J. Ovarian Res. 4:21.1-21.11(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4Z25
Encyclopedic resources Wikidata; Q54936908
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number14