Cellosaurus logo
expasy logo

Cellosaurus OV90C-D (CVCL_4Z24)

[Text][XML][JSON]
Cell line name OV90C-D
Accession CVCL_4Z24
Resource Identification Initiative To cite this cell line use: OV90C-D (RRID:CVCL_4Z24)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene fusion; HGNC; HGNC:1790; CDKN2D + HGNC; HGNC:20482; WDFY2; Name(s)=CDKN2D-WDFY2 (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Arg445Ter (c.1333C>T); ClinVar=VCV000024850; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser215Arg (c.643A>C); ClinVar=VCV000428895; Zygosity=Homozygous (from parent cell line).
Disease Ovarian adenocarcinoma (NCIt: C7700)
Adenocarcinoma of ovary (ORDO: Orphanet_213504)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3768 (OV-90)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=22141344; DOI=10.1186/1757-2215-4-21; PMCID=PMC3259089
Cheryl A. Sherman-Baust, Kevin G. Becker, William H. Wood 3rd, Yong-Qing Zhang, Patrice J. Morin;
Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin.
J. Ovarian Res. 4:21.1-21.11(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4Z24
Encyclopedic resources Wikidata; Q54936907
Entry history
Entry creation14-Dec-2015
Last entry update10-Apr-2025
Version number16