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Cellosaurus Hec50Co (CVCL_4Y59)

[Text version]
Cell line name Hec50Co
Synonyms HEC-50CO
Accession CVCL_4Y59
Resource Identification Initiative To cite this cell line use: Hec50Co (RRID:CVCL_4Y59)
Comments Population: Japanese.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:391; AKT1; Simple; p.Glu40Lys (c.118G>A); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
Disease Type II endometrial adenocarcinoma (NCIt: C39749)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2929 (HEC-50B)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=33174010

Markers:
AmelogeninX
CSF1PO9,12
D3S135815,16,17
D5S8188
D7S82012
D8S117910,15
D13S3179
D16S53912
D18S5114
D21S1130
FGA20
TH019
TPOX9
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=11830547
Dong-Hai Dai, Douglas M. Wolf, Elizabeth S. Litman, Michael J. White, Kimberly K. Leslie;
Progesterone inhibits human endometrial cancer cell growth and invasiveness: down-regulation of cellular adhesion molecules through progesterone B receptors.
Cancer Res. 62:881-886(2002)

PubMed=33174010; DOI=10.3892/ijo.2020.5139; PMCID=PMC8811471
Eric J. Devor, Jesus Gonzalez-Bosquet, Kristina W. Thiel, Kimberly K. Leslie;
Genomic characterization of five commonly used endometrial cancer cell lines.
Int. J. Oncol. 57:1348-1357(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4Y59
Encyclopedic resources Wikidata; Q54882270
Polymorphism and mutation databases Cosmic; 1393157
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number10