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Cellosaurus PC-3 D8 (CVCL_4Y41)

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Cell line name PC-3 D8
Accession CVCL_4Y41
Resource Identification Initiative To cite this cell line use: PC-3 D8 (RRID:CVCL_4Y41)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=21982118; DOI=10.1186/1476-4598-10-126; PMCID=PMC3203088
Amanda J. O'Neill, Maria Prencipe, Catherine Dowling, Yue Fan, Laoighse Mulrane, William M. Gallagher, Darran O'Connor, Robert O'Connor, Aoife Maire Devery, Claire Corcoran, Sweta Rani ...Show all 14 authors... , Lorraine O'Driscoll, John Michael Fitzpatrick, R. William G. Watson; Show fewer authors
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines.
Mol. Cancer 10:126.1-126.13(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4Y41
Encyclopedic resources Wikidata; Q54938408
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number12