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Cellosaurus SK-OV-3-Luc (CVCL_4Y20)

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Cell line name SK-OV-3-Luc
Accession CVCL_4Y20
Resource Identification Initiative To cite this cell line use: SK-OV-3-Luc (RRID:CVCL_4Y20)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1549

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S82014
D13S3178,11
D16S53912
TH019,9.3
TPOX8,11
vWA18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1549
JCRB; NIHS0737 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4Y20
Encyclopedic resources Wikidata; Q54954498
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number20