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Cellosaurus NCI-H650-Luc (CVCL_4Y16)

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Cell line name NCI-H650-Luc
Accession CVCL_4Y16
Resource Identification Initiative To cite this cell line use: NCI-H650-Luc (RRID:CVCL_4Y16)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser871Ter (c.2612C>A); ClinVar=VCV000051315; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6342; KIT; Simple; p.Pro41Glnfs*6 (c.121delC); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6342; KIT; Simple; p.Glu306Ter (c.916G>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000045116; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys164Asn (c.492G>T); Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1575 (NCI-H650)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1525

Markers:
AmelogeninX
CSF1PO10
D5S81811
D7S82010,11
D13S3178,12
D16S5398,11
TH016,9.3
TPOX8,11
vWA17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1525
JCRB; NIHS0729 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4Y16
Encyclopedic resources Wikidata; Q54908095
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number16