Cellosaurus cell line SW480/CMV-Luc (CVCL

Cross-references
Cell line name	SW480/CMV-Luc
Synonyms	SW-480/CMV-Luc
Accession	CVCL_4Y13
Resource Identification Initiative	To cite this cell line use: SW480/CMV-Luc (RRID:CVCL_4Y13)
Comments	Population: Caucasian. Characteristics: Expression of luciferase is under the control of the CMV promoter (JCRB=NIHS0738). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0546 (SW480)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Cell line collections (Providers)	JCRB; NIHS0738 - Discontinued
Cell line databases/resources	cancercelllines; CVCL_4Y13
Encyclopedic resources	Wikidata; Q54971168
Entry history
Entry creation	14-Dec-2015
Last entry update	14-Aug-2025
Version number	18