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Cellosaurus NCI-H23-Luc (CVCL_4W97)

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Cell line name NCI-H23-Luc
Accession CVCL_4W97
Resource Identification Initiative To cite this cell line use: NCI-H23-Luc (RRID:CVCL_4W97)
Comments Population: African American.
Karyotypic information: Has lost chromosome Y (from parent cell line).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Gln1919Pro (c.5756A>C); ClinVar=VCV000580726; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Trp332Ter (c.996G>A); ClinVar=VCV000376339; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Ile (c.738G>C); ClinVar=VCV001758655; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1547 (NCI-H23)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1509

Markers:
AmelogeninX
CSF1PO10
D5S81812,13
D7S8209,10
D13S31712
D16S53911
TH016
TPOX8,9
vWA16,17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1509
JCRB; NIHS0727 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4W97
Encyclopedic resources Wikidata; Q54907959
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number17