Cellosaurus cell line P388/NVB-2.5 (CVCL

Cross-references
Cell line name	P388/NVB-2.5
Synonyms	P388-N2.5; N2.5
Accession	CVCL_4W04
Resource Identification Initiative	To cite this cell line use: P388/NVB-2.5 (RRID:CVCL_4W04)
Comments	Selected for resistance to: ChEBI; CHEBI_480999; Vinorelbine (Navelbine; NVB). Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Disease	Mouse lymphoma (NCIt: C21602)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: DBA/2.
Hierarchy	Parent: CVCL_D640 (P388/S)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=11488526; DOI=10.1007/s002800100275 Chantal Etievant, Anna Kruczynski, Jean-Marc Barret, Alexandra S. Tait, Maria Kavallaris, Bridget T. Hill; Markedly diminished drug resistance-inducing properties of vinflunine (20',20'-difluoro-3',4'-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro. Cancer Chemother. Pharmacol. 48:62-70(2001) PubMed=18071633; DOI=10.1007/s10637-007-9102-3 Ashish Aggarwal, Anna Kruczynski, Anthony Frankfurter, John J. Correia, Sharon Lobert; Murine leukemia P388 vinorelbine-resistant cell lines are sensitive to vinflunine. Invest. New Drugs 26:319-330(2008)
Encyclopedic resources	Wikidata; Q54937268
Entry history
Entry creation	14-Dec-2015
Last entry update	14-Aug-2025
Version number	8