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Cellosaurus MOLP-2/R (CVCL_4V88)

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Cell line name MOLP-2/R
Accession CVCL_4V88
Resource Identification Initiative To cite this cell line use: MOLP-2/R (RRID:CVCL_4V88)
Comments Population: Japanese.
Characteristics: Produces IgD lambda.
Selected for resistance to: ChEBI; CHEBI_28876; Melphalan (L-phenylalanine mustard; LPAM; Alkeran).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala159Val (c.476C>T); ClinVar=VCV000458545; Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2123 (MOLP-2)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

DOI=10.1007/s10330-009-0051-5
Hui Xiao, Qi Xiao, Ke-Jian Zhang, Xue-Lan Zuo;
A novel myeloma cell line identified for multidrug resistant study.
Chinese-German J. Clin. Oncol. 8:296-299(2009)

PubMed=19756599; DOI=10.1007/s00277-009-0831-6
Hui Xiao, Qi Xiao, Ke-Jian Zhang, Xue-Lan Zuo, Umid Kumar Shrestha;
Reversal of multidrug resistance by curcumin through FA/BRCA pathway in multiple myeloma cell line MOLP-2/R.
Ann. Hematol. 89:399-404(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4V88
Encyclopedic resources Wikidata; Q54906335
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number14