Cellosaurus cell line SW620/L-OHP (CVCL

Cross-references
Cell line name	SW620/L-OHP
Accession	CVCL_4V77
Resource Identification Initiative	To cite this cell line use: SW620/L-OHP (RRID:CVCL_4V77)
Comments	Population: Caucasian. Selected for resistance to: ChEBI; CHEBI_31941; Oxaliplatin (Elotaxin; L-OHP). Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0547 (SW620)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Publications	PubMed=20591218; DOI=10.5732/cjc.009.10666 Zhen Liu, Meng Qiu, Qiu-Lin Tang, Ming Liu, Nan Lang, Feng Bi; Establishment and biological characteristics of oxaliplatin-resistant human colon cancer cell lines. Chin. J. Cancer 29:661-667(2010)
Cell line databases/resources	cancercelllines; CVCL_4V77
Encyclopedic resources	Wikidata; Q54971189
Entry history
Entry creation	14-Dec-2015
Last entry update	19-Dec-2024
Version number	17