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Cellosaurus SW620-OX (CVCL_4V76)

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Cell line name SW620-OX
Accession CVCL_4V76
Resource Identification Initiative To cite this cell line use: SW620-OX (RRID:CVCL_4V76)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_31941; Oxaliplatin (Elotaxin; L-OHP).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=24761924; DOI=10.7314/APJCP.2014.15.6.2911
Song Chian, Yin-Yan Li, Xiu-Jun Wang, Xiu-Wen Tang;
Luteolin sensitizes two oxaliplatin-resistant colorectal cancer cell lines to chemotherapeutic drugs via inhibition of the Nrf2 pathway.
Asian Pac. J. Cancer Prev. 15:2911-2916(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4V76
Encyclopedic resources Wikidata; Q54971187
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number17