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Cellosaurus K562/G01 (CVCL_4V47)

[Text version]
Cell line name K562/G01
Accession CVCL_4V47
Resource Identification Initiative To cite this cell line use: K562/G01 (RRID:CVCL_4V47)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_45783; Imatinib (Gleevec; STI571).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=15308010; DOI=10.3760/cma.j.issn.0253-2727.2004.06.007
Jing Qi, Hui Peng, Zhen-Lun Gu, Zhong-Qin Liang, Chun-Zheng Yang;
Establishment of an imatinib resistant cell line K562/G01 and its characterization.
Zhonghua Xue Ye Xue Za Zhi 25:337-341(2004)

Cross-references
Encyclopedic resources Wikidata; Q54899413
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number16