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Cellosaurus V79NHh1A2 (CVCL_4V40)

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Cell line name V79NHh1A2
Synonyms V79NH-h1A2; XEMhIA2-NH#1; XEMhIA2NH
Accession CVCL_4V40
Resource Identification Initiative To cite this cell line use: V79NHh1A2 (RRID:CVCL_4V40)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2596; CYP1A2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V38 (V79NH)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1446722; DOI=10.1016/0926-6917(92)90017-7
Catherine Wolfel, Barbara Heinrich-Hirsch, Thomas Schulz-Schalge, Albrecht Seidel, Heinz Frank, Uwe Ramp, Felix Wachter, Friedrich Johann Wiebel, Frank J. Gonzalez, Helmut Greim, Johannes Doehmer;
Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2.
Eur. J. Pharmacol. 228:95-102(1992)

PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Wolfgang A. Schmalix, Hildegard Maser, Franz Kiefer, Rashmeet Reen, Friedrich Johann Wiebel, Frank J. Gonzalez, Albrecht Seidel, Hans-Ruedolf Glatt, Helmut Greim, Johannes Doehmer;
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993)

Cross-references
Encyclopedic resources Wikidata; Q54992637
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number12