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Cellosaurus NCI-H2228-Luc (CVCL_4V13)

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Cell line name NCI-H2228-Luc
Accession CVCL_4V13
Resource Identification Initiative To cite this cell line use: NCI-H2228-Luc (RRID:CVCL_4V13)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Gene fusion; HGNC; HGNC:427; ALK + HGNC; HGNC:1316; EML4; Name(s)=EML4-ALK; Note=E6A20 v3 fusion (from parent cell line).
  • Gene fusion; HGNC; HGNC:427; ALK + HGNC; HGNC:9655; PTPN3; Name(s)=ALK-PTPN3 (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln331Ter (c.991C>T); ClinVar=VCV000922893; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1543 (NCI-H2228)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1492

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S82011
D13S31711
D16S53911,13
TH017,8
TPOX11
vWA15,17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1492
JCRB; NIHS0726 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4V13
Encyclopedic resources Wikidata; Q54907945
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number16