Cellosaurus logo
expasy logo

Cellosaurus A549(VP)28 (CVCL_4V07)

[Text version]
Cell line name A549(VP)28
Accession CVCL_4V07
Resource Identification Initiative To cite this cell line use: A549(VP)28 (RRID:CVCL_4V07)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:4911; Etoposide (VP-16).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=1717144
Long B.H., Wang L., Lorico A., Wang R.C.-C., Brattain M.G., Casazza A.M.
Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines.
Cancer Res. 51:5275-5283(1991)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4V07
Encyclopedic resources Wikidata; Q54607060
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number10