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Cellosaurus FUHEN (CVCL_4U91)

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Cell line name FUHEN
Synonyms Frog-derived Unique HEmatopoietic Non-adherent
Accession CVCL_4U91
Resource Identification Initiative To cite this cell line use: FUHEN (RRID:CVCL_4U91)
Comments Group: Amphibian cell line.
Doubling time: 197 hours (Note=At 28 Celsius) (PubMed=26322253).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Megakaryocyte; CL=CL_0000556.
Species of origin Dryophytes japonicus (Japanese tree frog) (Hyla japonica) (NCBI Taxonomy: 109175)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Web pages Provider; Niigata Univ.; -; https://www.sc.niigata-u.ac.jp/biologyindex/sugimoto/saranifuhen.html
Publications

PubMed=26322253; DOI=10.1186/s40064-015-1237-7; PMCID=PMC4547970
Kenkichi Sugimoto;
Establishment of a sticky, large, oval-shaped thrombocyte cell line from tree frog as an ancestor of mammalian megakaryocytes.
SpringerPlus 4:447.1-447.11(2015)

PubMed=34224189; DOI=10.1111/gtc.12882
Kenkichi Sugimoto, Kayano Toume;
Amphibian thrombocyte-derived extracellular vesicles, including microRNAs, induce angiogenesis-related genes in endothelial cells.
Genes Cells 26:757-771(2021)

Cross-references
Encyclopedic resources Wikidata; Q54835263
Entry history
Entry creation14-Dec-2015
Last entry update27-Nov-2025
Version number11