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Cellosaurus HuWa1 (CVCL_4U66)

[Text version]
Cell line name HuWa1
Synonyms Humpback Whale 1; HuWa; HuWa(wild-type)
Accession CVCL_4U66
Resource Identification Initiative To cite this cell line use: HuWa1 (RRID:CVCL_4U66)
Comments Group: Endangered species/breed cell line.
Group: Cetacean cell line.
Characteristics: Developed to test the toxicity of persistent organic pollutants (POPs) on marine mammals.
Doubling time: ~41 hours (PubMed=26363275).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Megaptera novaeangliae (Humpback whale) (Balaena novaeangliae) (NCBI Taxonomy: 9773)
Hierarchy Children:
CVCL_UJ99 (HuWa-TERT)CVCL_UK00 (HuWaTERT2)
Sex of cell Male
Age at sampling 1-2Y
Category Finite cell line
Web pages http://app.griffith.edu.au/sciencesimpact/whale-of-a-lab/
https://www.eawag.ch/en/department/utox/projects/humpback-whale-cell-lines/
Publications

PubMed=26363275; DOI=10.1016/j.aquatox.2015.08.005
Burkard M., Whitworth D.J., Schirmer K., Bengtson Nash S.M.
Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment.
Aquat. Toxicol. 167:240-247(2015)

CLPUB00462
Burkard M.
Humpback whale cell lines as an in vitro tool for toxicity assessment.
Thesis PhD (2017), Griffith School of Environment, Australia

PubMed=30627956; DOI=10.1007/s10565-018-09457-1
Burkard M., Bengtson Nash S.M., Gambaro G., Whitworth D.J., Schirmer K.
Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor).
Cell Biol. Toxicol. 35:387-398(2019)

Cross-references
Encyclopedic resources Wikidata; Q54896939
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number11