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Cellosaurus HROG17 (CVCL_4U45)

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Cell line name HROG17
Accession CVCL_4U45
Resource Identification Initiative To cite this cell line use: HROG17 (RRID:CVCL_4U45)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Doubling time: 32-43 hours (PubMed=23951083).
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; HLA class I peptidome.
Omics: Proteomics; HLA class II peptidome.
Derived from site: In situ; Brain, left parieto-occipital lobe.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Unspecified (CLS=300938).
HLA typing Source: PubMed=33592498
Class I
HLA-AA*11:01,66:01
HLA-BB*14:02,40:02
HLA-CC*01:02,08:02
Class II
HLA-DPDPA1*01:03,02:01
DPB1*04:01,11:01
HLA-DQDQA1*01:01,05:05
DQB1*03:01,05:01
HLA-DRDRB1*01:02,12:01
DRB3*02:02
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C6JX (HROG17-CIITA)
Originate from same individual CVCL_B7FQ ! HROG17 T1 M1
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): CLS=300938

Markers:
AmelogeninX
CSF1PO10,11
D1S165615,16
D2S133817,19
D3S135816,17
D5S81811,12
D6S104312,17
D7S8209,10
D8S117912,15
D12S39117,19.3
D13S3179,11
D16S53910,11
D18S5116,17
D19S43312,15
D21S1129,30
FGA25
Penta D9,15
Penta E7,20
TH019,9.3
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=23951083; DOI=10.1371/journal.pone.0071070; PMCID=PMC3737284
Christina Susanne Mullins, Bjorn Schneider, Florian Stockhammer, Mathias Krohn, Carl Friedrich Classen, Michael Linnebacher;
Establishment and characterization of primary glioblastoma cell lines from fresh and frozen material: a detailed comparison.
PLoS ONE 8:e71070.1-e71070.8(2013)

PubMed=33592498; DOI=10.1074/mcp.RA120.002201; PMCID=PMC8724627
Greta Forlani, Justine Michaux, HuiSong Pak, Florian Huber, Elodie Lauret Marie-Joseph, Elise Ramia, Brian J. Stevenson, Michael Linnebacher, Roberto S. Accolla, Michal Bassani-Sternberg;
CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens.
Mol. Cell. Proteomics 20:100032.1-100032.21(2021)

Cross-references
Cell line collections (Providers) CLS; 300938
Cell line databases/resources cancercelllines; CVCL_4U45
Encyclopedic resources Wikidata; Q54895317
Proteomic databases PRIDE; PXD020079
Entry history
Entry creation22-Sep-2015
Last entry update27-Nov-2025
Version number18