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Cellosaurus DLKP-Mitox (CVCL_4U31)

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Cell line name DLKP-Mitox
Synonyms DLKP-MITOX
Accession CVCL_4U31
Resource Identification Initiative To cite this cell line use: DLKP-Mitox (RRID:CVCL_4U31)
Comments Selected for resistance to: ChEBI; CHEBI_50729; Mitoxantrone.
Omics: Proteomics; 2DE-MS.
Donor information: Established from a patient that smoked approximately 40 cigarettes a day for most of his adult life (from parent cell line).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H737 (DLKP)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
Publications

PubMed=15239124; DOI=10.1002/ijc.20230
Yi-Zheng Liang, Lorraine O'Driscoll, Susan McDonnell, Padraig Doolan, Irene Oglesby, Kieran Duffy, Robert O'Connor, Martin Clynes;
Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.
Int. J. Cancer 111:484-493(2004)

PubMed=17593620
Lisa Murphy, Martin Clynes, Joanne Keenan;
Proteomic analysis to dissect mitoxantrone resistance-associated proteins in a squamous lung carcinoma.
Anticancer Res. 27:1277-1284(2007)

Cross-references
Encyclopedic resources Wikidata; Q54831183
Entry history
Entry creation22-Sep-2015
Last entry update14-Aug-2025
Version number12