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Cellosaurus AG07671 (CVCL_4P39)

[Text version]
Cell line name AG07671
Synonyms AG 7671; AG07671A
Accession CVCL_4P39
Resource Identification Initiative To cite this cell line use: AG07671 (RRID:CVCL_4P39)
Comments Part of: Canadian Alzheimer disease kindred subcollection.
Population: Caucasian.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 9508; PSEN1; Simple; p.Ala246Glu (c.737C>A); ClinVar=VCV000018125; Zygosity=Unspecified (PubMed=24416243).
Disease Alzheimer's disease 3 (NCIt: C123412)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_AD13 (NYSCF-AD-1015-AG07671-Skin-RV-IPSC1)
Originate from same individual CVCL_4P38 ! AG07670
Sex of cell Male
Age at sampling 44Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994)

PubMed=8643543; DOI=10.1073/pnas.93.10.5146
Parshad R., Sanford K.K., Price F.M., Melnick L.K., Nee L.E., Schapiro M.B., Tarone R.E., Robbins J.H.
Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture.
Proc. Natl. Acad. Sci. U.S.A. 93:5146-5150(1996)

Patent=US5773219
Sanford K.K., Parshad R., Robbins J.H.
Process for detecting Alzheimer disease using cultured cells.
Patent number US5773219, 30-Jun-1998

PubMed=24416243; DOI=10.1371/journal.pone.0084547
Sproul A.A., Jacob S., Pre D., Kim S.H., Nestor M.W., Navarro-Sobrino M., Santa-Maria I., Zimmer M., Aubry S., Steele J.W., Kahler D.J., Dranovsky A., Arancio O., Crary J.F., Gandy S.E., Noggle S.A.
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors.
PLoS ONE 9:E84547-E84547(2014)

Cross-references
Cell line collections (Providers) Coriell; AG07671
Cell line databases/resources CLO; CLO_0032907
Encyclopedic resources Wikidata; Q54741044
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number11