Cellosaurus cell line AG07613 (CVCL

Cellosaurus AG07613 (CVCL_4N94)

Cross-references
Cell line name	AG07613
Synonyms	AG07613A; AG 7613A; AG07613B
Accession	CVCL_4N94
Resource Identification Initiative	To cite this cell line use: AG07613 (RRID:CVCL_4N94)
Comments	Part of: Canadian Alzheimer disease kindred subcollection. Population: Caucasian. Doubling time: Slow growth (Coriell=AG07613). Karyotypic information: 46,XY,inv(Y)(pter->p11.2::q12->p11.2::q12->qter) (Coriell=AG07613). Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:9508; PSEN1; Simple; p.Ala246Glu (c.737C>A); ClinVar=VCV000018125; Zygosity=Unspecified (from inference of kindred).
Disease	Alzheimer's disease 3 (NCIt: C123412) Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_4N95 ! AG07614
Sex of cell	Male
Age at sampling	66Y
Category	Finite cell line
Publications	CLPUB00597 National Institute on Aging 1994 catalog of cell lines. NIA Aging Cell Repository. (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994) PubMed=8643543; DOI=10.1073/pnas.93.10.5146; PMCID=PMC39422 Ram Parshad, Katherine Koontz Sanford, Floyd M. Price, Lynn K. Melnick, Linda E. Nee, Mark B. Schapiro, Robert E. Tarone, Jay H. Robbins; Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture. Proc. Natl. Acad. Sci. U.S.A. 93:5146-5150(1996) Patent=US5773219 Katherine Koontz Sanford, Ram Parshad, Jay H. Robbins; Process for detecting Alzheimer disease using cultured cells. Patent number US5773219, 30-Jun-1998
Cell line collections (Providers)	Coriell; AG07613
Cell line databases/resources	CLO; CLO_0032828
Encyclopedic resources	Wikidata; Q54740874
Entry history
Entry creation	22-Sep-2015
Last entry update	19-Dec-2024
Version number	13