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Cellosaurus HBEC-5i (CVCL_4D10)

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Cell line name HBEC-5i
Synonyms HBEC5i; Human Brain Endothelial Cell line-5i
Accession CVCL_4D10
Resource Identification Initiative To cite this cell line use: HBEC-5i (RRID:CVCL_4D10)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brain, cerebral cortex; UBERON=UBERON_0000956.
Cell type: Brain microvascular endothelial cell; CL=CL_2000044.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): AddexBio=T0005011/5009; ATCC=CRL-3245

Markers:
AmelogeninX,Y
CSF1PO11,13
D5S81811,13
D7S82011
D13S3179,12
D16S53910,13
TH016,9.3
TPOX8,11
vWA14,18

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Publications

PubMed=16369021; DOI=10.1128/IAI.74.1.645-653.2006; PMCID=PMC1346683
Samuel Crocodile Wassmer, Valery Combes, Francisco J. Candal, Irene Juhan-Vague, Georges E. Grau;
Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum.
Infect. Immun. 74:645-653(2006)

PubMed=30240829; DOI=10.1016/j.ijpharm.2018.09.040
Clementine Puech, Sophie Hodin, Valerie Forest, Zhi-Guo He, Patrick Mismetti, Xavier Delavenne, Nathalie Perek;
Assessment of HBEC-5i endothelial cell line cultivated in astrocyte conditioned medium as a human blood-brain barrier model for ABC drug transport studies.
Int. J. Pharm. 551:281-289(2018)

Cross-references
Cell line collections (Providers) AddexBio; T0005011/5009
ATCC; CRL-3245
Encyclopedic resources Wikidata; Q54881382
Entry history
Entry creation22-Sep-2015
Last entry update02-May-2024
Version number11