| Cell line name |
MCF-7/CG-5 |
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| Synonyms |
CG-5; CG5 |
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| Accession |
CVCL_4D04 |
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| Resource Identification Initiative |
To cite this cell line use: MCF-7/CG-5 (RRID:CVCL_4D04) |
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| Comments |
Population: Caucasian.
Characteristics: Estrogen supersensitive (PubMed=6575841).
Doubling time: 13 hours (PubMed=8712686).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Invasive breast carcinoma of no special type (NCIt: C4194) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0031 (MCF-7)
Children:
|
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| Sex of cell |
Female |
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| Age at sampling |
69Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=6575841; DOI=10.1007/BF01806231
Clara Natoli, Gigliola Sica, Vittoria Natoli, Angelo Serra, Stefano Iacobelli;
Two new estrogen-supersensitive variants of the MCF-7 human breast cancer cell line.
Breast Cancer Res. Treat. 3:23-32(1983) PubMed=3516389
Stefano Iacobelli, Elena Arno, Alfonso D'Orazio, Gino Coletti;
Detection of antigens recognized by a novel monoclonal antibody in tissue and serum from patients with breast cancer.
Cancer Res. 46:3005-3010(1986) PubMed=8712686
Nadia Gibelli, Carol Zibera, Annalia Asti, Luciano Maestri, Luisa Bacchella, Paolo Pedrazzoli, Alberto Calligaro, Gioacchino Robustelli della Cuna;
CG5/Dx human breast cancer cell line: characterization of a new doxorubicin-resistant variant.
Anticancer Res. 16:1675-1681(1996) |
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| Cross-references |
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| Cell line databases/resources |
CLO; CLO_0002398
cancercelllines; CVCL_4D04
|
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| Encyclopedic resources |
Wikidata; Q54904360
|
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| Entry history |
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| Entry creation | 22-Sep-2015 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 16 |
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