Cellosaurus logo
expasy logo

Cellosaurus PC-93 (CVCL_4888)

[Text version]
Cell line name PC-93
Accession CVCL_4888
Resource Identification Initiative To cite this cell line use: PC-93 (RRID:CVCL_4888)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=14518029; PubMed=20143388). Originally thought to originate from a moderately differentiated primary adenocarcinoma of the prostate.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00256.
Population: African American.
Doubling time: 20 hours (PubMed=6602397).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=6602397; DOI=10.1111/j.1399-0039.1983.tb00162.x
Franciscus H.J. Claas, Gert Jan van Steenbrugge;
Expression of HLA-like structures on a permanent human tumor line PC-93.
Tissue Antigens 21:227-232(1983)

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Pamela J. Russell, Elizabeth A. Kingsley;
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=14518029; DOI=10.1002/pros.10290
Adrie van Bokhoven, Marileila Varella-Garcia, Christopher T. Korch, Widya U. Johannes, E. Erin Smith, Heidi L. Miller, Steven K. Nordeen, Gary J. Miller, M. Scott Lucia;
Molecular characterization of human prostate carcinoma cell lines.
Prostate 57:205-225(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151752
Encyclopedic resources Wikidata; Q54086637
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23