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Cellosaurus PC-3-1A (CVCL_4877)

[Text version]
Cell line name PC-3-1A
Accession CVCL_4877
Resource Identification Initiative To cite this cell line use: PC-3-1A (RRID:CVCL_4877)
Comments Population: Caucasian.
Characteristics: Established from tumors obtained after subcutaneous injection of the parent cell line in nude mice (PubMed=7176035).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line

PubMed=7176035; DOI=10.1016/S0022-5347(17)53345-5
Ware J.L., Paulson D.F., Mickey G.H., Webb K.S.
Spontaneous metastasis of cells of the human prostate carcinoma cell line PC-3 in athymic nude mice.
J. Urol. 128:1064-1067(1982)

PubMed=15643172; DOI=10.1097/01.ju.0000141580.30910.57
Sobel R.E., Sadar M.D.
Cell lines used in prostate cancer research: a compendium of old and new lines -- part 1.
J. Urol. 173:342-359(2005)

Cell line databases/resources cancercelllines; CVCL_4877
Encyclopedic resources Wikidata; Q54938414
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18