Cellosaurus cell line ECPC-4 (CVCL

Cellosaurus ECPC-4 (CVCL_4836)

Cross-references
Cell line name	ECPC-4
Synonyms	ECPC4
Accession	CVCL_4836
Resource Identification Initiative	To cite this cell line use: ECPC-4 (RRID:CVCL_4836)
Comments	Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Omics: Proteomics; 2DE-MS. Derived from site: In situ; Brain, choroid plexus; UBERON=UBERON_0001886.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 IgH-T-Ag transgenic.
Originate from same individual	CVCL_4835 ! ECPC-3
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=8878450; DOI=10.1111/j.1349-7006.1996.tb02117.x; PMCID=PMC5921209 Munechika Enjoji, Toru Iwaki, Hideo Hara, Hironori Sakai, Hajime Nawata, Takeshi Watanabe; Establishment and characterization of choroid plexus carcinoma cell lines: connection between choroid plexus and immune systems. Jpn. J. Cancer Res. 87:893-899(1996) PubMed=26794622; DOI=10.1007/s00011-016-0916-3 Masaoki Takano, Mieko Otani, Takahiro Kaji, Keiji Sano, Michiko Hamada-Kanazawa, Shogo Matsuyama; Proteomic analysis of mouse choroid plexus cell line ECPC-4 treated with lipid A. Inflamm. Res. 65:295-302(2016) PubMed=26833402; DOI=10.1186/s12987-016-0027-0; PMCID=PMC4734852 Ivana Lazarevic, Britta Engelhardt; Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier. Fluids Barriers CNS 13:2.1-2.20(2016)
Cell line collections (Providers)	RCB; RCB1287
Cell line databases/resources	CLO; CLO_0050205
Encyclopedic resources	Wikidata; Q54831942
Entry history
Entry creation	04-Apr-2012
Last entry update	14-Aug-2025
Version number	17