Cellosaurus logo
expasy logo

Cellosaurus ACH-3P (CVCL_4829)

[Text][XML][JSON]
Cell line name ACH-3P
Synonyms ACH 3P
Accession CVCL_4829
Resource Identification Initiative To cite this cell line use: ACH-3P (RRID:CVCL_4829)
Comments Characteristics: Fusion of the AC1-1 choriocarcinoma cell line with primary first trimester trophoblasts (week 12 of gestation) (PubMed=18093301).
Doubling time: 2.74 +- 0.35 days (PubMed=28724925).
Karyotypic information: Near tetraploid karyotype (PubMed=33096371).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9560 (AC1-1)
Category Hybrid cell line
STR profile Source(s): PubMed=33810901

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D1S165614,16
D2S44110,12,14
D2S133820,22,24
D3S135815,16,18
D5S81810,11
D7S82010,12,13
D8S117912
D10S124813,14,15
D12S39117,19,21,24
D13S3179,11
D16S53912,13,14
D18S5113,14,15
D19S43313,15
D21S1130,31
D22S104515,16
FGA21,22,23
Penta D8,9,12,14
Penta E5,8,12
SE3315,36
TH019,9.3
TPOX8,11,12
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=18093301; DOI=10.1186/1471-213X-7-137; PMCID=PMC2263055
Ursula Hiden, Christian Wadsack, Nicole Prutsch, Martin Gauster, Ursula Weiss, Hans-Georg Frank, Ulrike Schmitz, Christa Fast-Hirsch, Markus Hengstschlager, Andre J.G. Potgens, Angela Ruben ...Show all 17 authors... , Martin Knofler, Peter Haslinger, Berthold Huppertz, Martin Bilban, Peter Kaufmann, Gernot Desoye; Show fewer authors
The first trimester human trophoblast cell line ACH-3P: a novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations -- TNF-alpha stimulates MMP15 expression.
BMC Dev. Biol. 7:137.1-137.13(2007)

PubMed=28724925; DOI=10.1038/s41598-017-06364-z; PMCID=PMC5517571
Mario Rothbauer, Nilaykumar Patel, Hajnalka Gondola, Monika Siwetz, Berthold Huppertz, Peter Ertl;
A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci. Rep. 7:5892.1-5892.11(2017)

PubMed=33096371; DOI=10.1016/j.placenta.2020.10.011
Maja Weber, Anja Weise, Faezeh Vasheghani, Claudia Gohner, Justine Sayuri Fitzgerald, Thomas Liehr, Udo R. Markert;
Cytogenomics of six human trophoblastic cell lines.
Placenta 103:72-75(2021)

PubMed=33810901; DOI=10.1016/j.placenta.2021.02.022
Jana Pastuschek, Olivia Nonn, Ruby N. Gutierrez-Samudio, Jose Martin Murrieta-Coxca, Jasmin Muller, Juliane Sanft, Berthold Huppertz, Udo R. Markert, Tanja Groten, Diana M. Morales-Prieto;
Molecular characteristics of established trophoblast-derived cell lines.
Placenta 108:122-133(2021)

Cross-references
Anatomy/cell type resources BTO; BTO_0003421
Encyclopedic resources Wikidata; Q54608363
Experimental variables resources EFO; EFO_0006269
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number12