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Cellosaurus 267B1 (CVCL_4827)

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Cell line name 267B1
Synonyms 267-B1; 267 B1; FNC267B1
Accession CVCL_4827
Resource Identification Initiative To cite this cell line use: 267B1 (RRID:CVCL_4827)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_9871 (267B1/Ki-ras)CVCL_F0TR (267B1/X)
Originate from same individual CVCL_K058 ! 272E1
CVCL_K059 ! 272E4
Sex of cell Male
Age at sampling <1D
Category Transformed cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160703200507/http://capcelllines.ca:80/details.asp?id=131
Publications

PubMed=2541897
M. Edward Kaighn, Roger Robert Reddel, John F. Lechner, Donna M. Peehl, Richard F. Camalier, Douglas E. Brash, Umberto Saffiotti, Curtis Craig Harris;
Transformation of human neonatal prostate epithelial cells by strontium phosphate transfection with a plasmid containing SV40 early region genes.
Cancer Res. 49:3050-3056(1989)

PubMed=8378190; DOI=10.1002/pros.2990230202
David S. Parda, Peter J. Thraves, Michael R. Kuettel, Myeong-Seon Lee, Paul Arnstein, M. Edward Kaighn, Johng Sik Rhim, Anatoly Dritschilo;
Neoplastic transformation of a human prostate epithelial cell line by the v-Ki-ras oncogene.
Prostate 23:91-98(1993)

PubMed=8548774
Michael R. Kuettel, Peter J. Thraves, Mira Jung, Susan P. Varghese, Sarada C. Prasad, Johng Sik Rhim, Anatoly Dritschilo;
Radiation-induced neoplastic transformation of human prostate epithelial cells.
Cancer Res. 56:5-10(1996)

PubMed=9772298; DOI=10.3892/ijo.13.5.1043
Angelika Maria Burger, Heinz-Herbert Fiebig, Michael R. Kuettel, James Allen Lautenberger, Hsiang-Fu Kung, Johng Sik Rhim;
Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells.
Int. J. Oncol. 13:1043-1048(1998)

PubMed=12085227; DOI=10.1038/sj.onc.1205547
Bo-Yeon Kim, Richard Brian Gaynor, Kyung Song, Anatoly Dritschilo, Mira Jung;
Constitutive activation of NF-kappaB in Ki-ras-transformed prostate epithelial cells.
Oncogene 21:4490-4497(2002)

Cross-references
Cell line databases/resources FCS-free; 15-2-16-3-6-4
Encyclopedic resources Wikidata; Q54583693
Experimental variables resources EFO; EFO_0001080
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number18