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Cellosaurus 1542-CPTX-1 (CVCL_4821)

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Cell line name 1542-CPTX-1
Synonyms 1542-CP1TX; 1542T
Accession CVCL_4821
Resource Identification Initiative To cite this cell line use: 1542-CPTX-1 (RRID:CVCL_4821)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4822 ! 1542-CPTX-2
CVCL_4823 ! 1542-CPTX-3
CVCL_4824 ! 1542-normal
CVCL_4825 ! 1542-seminal vesicle
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160703200804/http://capcelllines.ca:80/details.asp?id=99
Publications

PubMed=9041206
Robert K. Bright, Cathy D. Vocke, Michael R. Emmert-Buck, Paul H. Duray, Diane Solomon, Patricia A. Fetsch, Johng Sik Rhim, William Marston Linehan, Suzanne Louise Topalian;
Generation and genetic characterization of immortal human prostate epithelial cell lines derived from primary cancer specimens.
Cancer Res. 57:995-1002(1997)

PubMed=10913677; DOI=10.1016/S0165-4608(99)00248-4
Jill A. Macoska, Ben Beheshti, Johng Sik Rhim, Bharati Hukku, Jeff Lehr, Kenneth James Pienta, Jeremy Andrew Squire;
Genetic characterization of immortalized human prostate epithelial cell cultures. Evidence for structural rearrangements of chromosome 8 and i(8q) chromosome formation in primary tumor-derived cells.
Cancer Genet. Cytogenet. 120:50-57(2000)

PubMed=16235240; DOI=10.1002/gcc.20274
Lesa Begley, David Keeney, Ben Beheshti, Jeremy Andrew Squire, Rajiv Kant, Hassan Chaib, James W. MacDonald, Johng Sik Rhim, Jill A. Macoska;
Concordant copy number and transcriptional activity of genes mapping to derivative chromosomes 8 during cellular immortalization in vitro.
Genes Chromosomes Cancer 45:136-146(2006)

Cross-references
Encyclopedic resources Wikidata; Q54582092
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number16