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Cellosaurus XG-4 (CVCL_4800)

[Text version]
Cell line name XG-4
Synonyms XG4; XG 4
Accession CVCL_4800
Resource Identification Initiative To cite this cell line use: XG-4 (RRID:CVCL_4800)
Comments Characteristics: Produces IgG kappa.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
Publications

PubMed=1753108; DOI=10.4049/jimmunol.147.12.4402
Michel Jourdan, Xue-Guang Zhang, Marielle Portier, Jean-Michel Boiron, Francois-Regis Bataille, Bernard Klein;
IFN-alpha induces autocrine production of IL-6 in myeloma cell lines.
J. Immunol. 147:4402-4407(1991)

PubMed=1373872
Georges-Raoul Mazars, Marielle Portier, Xue-Guang Zhang, Michel Jourdan, Francois-Regis Bataille, Charles Theillet, Bernard Klein;
Mutations of the p53 gene in human myeloma cell lines.
Oncogene 7:1015-1018(1992)

PubMed=8204890; DOI=10.1182/blood.V83.12.3654.3654
Xue-Guang Zhang, Jean-Philippe Gaillard, Nelly Robillard, Zhao-Yang Lu, Zong-Jiang Gu, Michel Jourdan, Jean-Michel Boiron, Francois-Regis Bataille, Bernard Klein;
Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma.
Blood 83:3654-3663(1994)

PubMed=10557056; DOI=10.1038/sj.leu.2401563
S. Yoshida, Naozo Nakazawa, S. Iida, Yoshihito Hayami, S. Sato, Atsushi Wakita, S. Shimizu, Masafumi Taniwaki, R. Ueda;
Detection of MUM1/IRF4-IgH fusion in multiple myeloma.
Leukemia 13:1812-1816(1999)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=21173094; DOI=10.3324/haematol.2010.033456; PMCID=PMC3069235
Jerome Moreaux, Bernard Klein, Francois-Regis Bataille, Geraldine Descamps, Sophie Maiga, Dirk Hose, Hartmut Goldschmidt, Anna Jauch, Thierry Reme, Michel Jourdan, Martine Amiot, Catherine Pellat-Deceunynck;
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Haematologica 96:574-582(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4800
Encyclopedic resources Wikidata; Q54994712
Gene expression databases ArrayExpress; E-TABM-937
Polymorphism and mutation databases Cosmic; 742961
IARC_TP53; 364
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number23