Cellosaurus logo
expasy logo

Cellosaurus LNCaP-Rf (CVCL_4792)

[Text][XML][JSON]
Cell line name LNCaP-Rf
Synonyms LNCaP-RF
Accession CVCL_4792
Resource Identification Initiative To cite this cell line use: LNCaP-Rf (RRID:CVCL_4792)
Comments Population: Caucasian.
Doubling time: 34.14 hours (JWGray panel).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0395 (LNCaP)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160322000315/http://capcelllines.ca/details.asp?id=175
Publications

PubMed=11861374
Ofelia L. Zegarra-Moro, Lucy J. Schmidt, Hao-Jie Huang, Donald J. Tindall;
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells.
Cancer Res. 62:1008-1013(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4792
Encyclopedic resources Wikidata; Q54902853
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22