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Cellosaurus LNCaP C4-2B2 (CVCL_4785)

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Cell line name LNCaP C4-2B2
Synonyms LNCaP-C4-2 B2; C4-2B2; Sp 2815
Accession CVCL_4785
Resource Identification Initiative To cite this cell line use: LNCaP C4-2B2 (RRID:CVCL_4785)
Comments Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4784 (LNCaP C4-2B)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160703200703/http://capcelllines.ca:80/details.asp?id=165
Publications

PubMed=10881018; DOI=10.1002/1097-0045(20000701)44:2<91::AID-PROS1>3.0.CO;2-L
George Niklaus Thalmann, Robert A. Sikes, Tony T. Wu, Armelle Degeorges, Shi-Ming Chang, Mustafa Ozen, Sen Pathak, Leland W.K. Chung;
LNCaP progression model of human prostate cancer: androgen-independence and osseous metastasis.
Prostate 44:91-103(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4785
Encyclopedic resources Wikidata; Q54902816
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number21