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Cellosaurus KU-7 (CVCL_4714)

[Text version]
Cell line name KU-7
Synonyms KU7; Keio University-7
Accession CVCL_4714
Resource Identification Initiative To cite this cell line use: KU-7 (RRID:CVCL_4714)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=23500642). Was thought to originate from an urinary bladder papillary carcinoma.
Part of: BLA-40 bladder carcinoma cell line panel.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00480.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
CVCL_M894 (KU-7-luc2-GFP)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://retractionwatch.com/2013/03/11/more-hela-problems-for-decades-a-widely-used-bladder-cancer-line-hasnt-been-what-scientists-thought/

PubMed=7185004; DOI=10.2302/kjm.31.127
Tachibana M.
Studies on cellular adhesiveness in five different culture cell lines derived from carcinoma of the urinary bladder.
Keio J. Med. 31:127-148(1982)

Tazaki H., Tachibana M.
Studies on KU-1 and KU-7 cells as an in vitro model of human transitional cell carcinoma of urinary bladder.
Hum. Cell 1:78-83(1988)

PubMed=19375735; DOI=10.1016/j.juro.2009.01.108
Chiong E., Dadbin A., Harris L.D., Sabichi A.L., Grossman H.B.
The use of short tandem repeat profiling to characterize human bladder cancer cell lines.
J. Urol. 181:2737-2748(2009)

PubMed=23500642; DOI=10.1016/j.juro.2013.03.009
Jager W., Horiguchi Y., Shah J., Hayashi T., Awrey S., Gust K.M., Hadaschik B.A., Matsui Y., Anderson S., Bell R.H., Ettinger S., So A.I., Gleave M.E., Lee I.-L., Dinney C.P.N., Tachibana M., McConkey D.J., Black P.C.
Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa.
J. Urol. 190:1404-1409(2013)

Anatomy/cell type resources BTO; BTO:0003544
Biological sample resources BioSample; SAMN03151734
Encyclopedic resources Wikidata; Q54900675
Gene expression databases GEO; GSM136238
Polymorphism and mutation databases Cosmic; 1082646
Cosmic; 1302356
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23