Cellosaurus cell line BLSC-KU-1 (CVCL

Cellosaurus BLSC-KU-1 (CVCL_4711)

Cross-references
Cell line name	BLSC-KU-1
Synonyms	BLSC-KU1; KU-1
Accession	CVCL_4711
Secondary accession	CVCL_F545
Resource Identification Initiative	To cite this cell line use: BLSC-KU-1 (RRID:CVCL_4711)
Comments	Virology: Contains a single copy of a defective provirus with approximately 1.7 kbp deleted from the C-terminal of the pol gene to most of the env-gp51 gene. The provirus is integrated in a an intron of the RPTOR gene (PubMed=35632737). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236.
Disease	Bovine leukemia (NCIt: C131469)
Species of origin	Bos taurus (Bovine) (NCBI Taxonomy: 9913) Breed/subspecies: Japanese black; VBO=VBO_0004987.
Sex of cell	Female
Age at sampling	4Y
Category	Cancer cell line
Publications	PubMed=3012214; DOI=10.1016/0145-2126(86)90274-2 Misao Onuma, Hiroyuki Koyama, Yoko Aida, Kosuke Okada, Yasuki Ogawa, Rikio Kirisawa, Yoshimi Kawakami; Establishment of B-cell lines from tumor of enzootic bovine leukosis. Leuk. Res. 10:689-695(1986) PubMed=3026121; DOI=10.1111/j.1439-0450.1986.tb00073.x Hiroyuki Koyama, Yasutaka Imamura, Hiroyasu Yoshikawa, Osamu Kajikawa, Shigeyoshi Itohara, Yoshio Mizuno, Takashi Yoshikawa, Hiroshi Saito; Establishment of a continuous cell line derived from leukaemic cattle. Zentralbl. Veterinarmed. B 33:586-596(1986) PubMed=35632737; DOI=10.3390/v14050995; PMCID=PMC9143949 Meripet Polat Yamanaka, Susumu Saito, Kazuyoshi Hosomichi, Yoko Aida; Comprehensive comparison of novel bovine leukemia virus (BLV) integration sites between B-cell lymphoma lines BLSC-KU1 and BLSC-KU17 using the viral DNA capture high-throughput sequencing method. Viruses 14:995.1-995.17(2022)
Cell line collections (Providers)	RCB; RCB0417
Cell line databases/resources	CLO; CLO_0050470
Encyclopedic resources	Wikidata; Q54797426
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Sep-2024
Version number	12