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Cellosaurus RLE-6TN (CVCL_4693)

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Cell line name RLE-6TN
Synonyms Rat Lung Epithelial-6-T-antigen Negative
Accession CVCL_4693
Resource Identification Initiative To cite this cell line use: RLE-6TN (RRID:CVCL_4693)
Comments Characteristics: While transfected with SV40 pRSV-T, does not express SV40 T antigen thus said to be derived from a spontaneous transformant.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Originate from same individual CVCL_LB71 ! RLE-6T
Sex of cell Male
Age at sampling 56D
Category Transformed cell line
Publications

PubMed=8528500; DOI=10.1007/BF02634029
Kevin E. Driscoll, Janet M. Carter, Pullolickal Thomas Iype, H. Lalitha Kumari, Leslie L. Crosby, Marilyn J. Aardema, Robert J. Isfort, David Cody, Matthew H. Chestnut, Janet L. Burns, Robert A. LeBoeuf;
Establishment of immortalized alveolar type II epithelial cell lines from adult rats.
In Vitro Cell. Dev. Biol. Anim. 31:516-527(1995)

PubMed=12740220; DOI=10.1152/ajplung.00376.2002
Jian-Xun Lei, Sogol Nowbar, Cary N. Mariash, David H. Ingbar;
Thyroid hormone stimulates Na-K-ATPase activity and its plasma membrane insertion in rat alveolar epithelial cells.
Am. J. Physiol. Lung Cell. Mol. Physiol. 285:L762-L772(2003)

Cross-references
Cell line collections (Providers) AddexBio; C0016014/4948
ATCC; CRL-2300
IZSLER; BS CL 206
Cell line databases/resources CLO; CLO_0008835
Anatomy/cell type resources BTO; BTO_0003510
Encyclopedic resources Wikidata; Q54950601
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number21