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Cellosaurus pgsD-677 (CVCL_4593)

[Text version]
Cell line name pgsD-677
Synonyms PgsD-677 pgsD677; 677; Mutant 677; CHO-677; CHO 677
Accession CVCL_4593
Resource Identification Initiative To cite this cell line use: pgsD-677 (RRID:CVCL_4593)
Comments Characteristics: Lacks both N-acetylglucosaminyltransferase and glucuronyltransferase activities that are required for synthesis of heparan sulfate.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1532254; DOI=10.1073/pnas.89.6.2267; PMCID=PMC48638
Kerstin Lidholt, Julie L. Weinke, Cheryl S. Kiser, Fulgentius Nelson Lugemwa, Karen J. Bame, Sela Cheifetz, Joan Massague, Ulf Lindahl, Jeffrey David Esko;
A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis.
Proc. Natl. Acad. Sci. U.S.A. 89:2267-2271(1992)

Cross-references
Cell line collections (Providers) ATCC; CRL-2244
Cell line databases/resources CLO; CLO_0008438
Encyclopedic resources Wikidata; Q54947334
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number11