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Cellosaurus (CVCL_4580)

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Comments Doubling time: 32 +- 9 hours (PubMed=856461); ~100 hours (DSMZ=ACC-655); ~2 days (ECACC=06041201).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): COG; DSMZ=ACC-655; ECACC=06041201; RCB=RCB0483

Markers:
AmelogeninX,Y
CSF1PO12
D13S31711,12
D16S5399
D18S5114
D19S43313
D21S1129,36
D2S133816,21
D3S135816,16.2
D5S81812
D7S82010 (COG)
10,11 (DSMZ=ACC-655; ECACC=06041201; RCB=RCB0483)
D8S117913,14
FGA19,24
Penta D9,13
Penta E11,12
TH018,9.3
TPOX8,11
vWA16,19

Run an STR similarity search on this cell line
Publications






carcinogen-transformed guinea pig cells.
Cancer Res. 36:1404-1413(1976)


Michael G. Brattain, W. David Fine, F. Mahnaz Khaled, Jerry Thompson, Diane E. Brattain;
Heterogeneity of malignant cells from a human colonic carcinoma.
Cancer Res. 41:1751-1756(1981)




(In book chapter) Cold Spring Harbor conferences on cell proliferation: teratocarcinoma stem cells, Vol. 10; Silver, Lee Merrill & Martin, Gail Roberta & Strickland, Sidney (eds.); pp.597-605; Cold Spring Harbor Laboratory Press; New York; USA (1983)


Susan A. Harcourt, Herdis Steingrimsdottir, Miria Stefanini, Alexander Malcolm R. Taylor, Adayapalam Thyagarajan Natarajan, Stuart Green, Mary D. King, Rona McLeod MacKie, John Burdett Primmer Stephenson, John Lorimer Tolmie;
Trichothiodystrophy, a human DNA repair disorder with heterogeneity in the cellular response to ultraviolet light.
Cancer Res. 48:6090-6096(1988)



subunit is inhibited in c-erbB2-transfected human mammary epithelial cells.
Oncogene 8:1797-1806(1993)




Am. J. Pathol. 161:207-216(2002)



Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2).
Genes Chromosomes Cancer 37:84-91(2003)


Harith Rajagopalan, Prasad V. Jallepalli, Carlo Rago, Victor E. Velculescu, Kenneth Wayne Kinzler, Bert Vogelstein, Christoph Lengauer;
Inactivation of hCDC4 can cause chromosomal instability.
Nature 428:77-81(2004)


Masahiko Hatano, Makoto Matsui, Akitsugu Yamamoto, Haruaki Nakaya, Tamotsu Yoshimori, Yoshinori Ohsumi, Takeshi Tokuhisa, Noboru Mizushima;
The role of autophagy during the early neonatal starvation period.
Nature 432:1032-1036(2004)



Genes that mediate breast cancer metastasis to lung.
Nature 436:518-524(2005)



progression.
Cell 132:487-498(2008)




BMC Biotechnol. 9:89.1-89.15(2009)


Paula D. Bos, Xiang H.-F. Zhang, Cristina Nadal, Wei-Ping Shu, Roger R. Gomis, Don X. Nguyen, Andy J. Minn, Marc Joan van de Vijver, William Levi Gerald, John A. Foekens, Joan Massague;
Genes that mediate breast cancer metastasis to the brain.
Nature 459:1005-1009(2009)


Antony Wilks Burgess;
Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Int. J. Cancer 125:297-307(2009)



tumor growth resumption.
Thesis PhD (2020); Ludwig Maximilians University of Munich; Munich; Germany


Hiroyuki Ito, Soichiro Morinaga, Takeshi Kishida, Toshinari Minamoto, Shinji Yamada, Junko Takei, Mika Kato Kaneko, Motohiro Kojima, Shuichi Kaneko, Tsutomu Masaki, Masahiro Hirata ...Show all 18 authors... , Reiji Haba, Keiichi Kontani, Nobuhiro Kanaji, Nobuyuki Miyatake, Keiichi Okano, Yukinari Kato, Kenkichi Masutomi; Show fewer authors
Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs.
J. Pathol. 257:172-185(2022)

Cross-references
Cell line collections (Providers) DSMZ; ACC-655
ECACC; 06041201
ICLC; HTL98005 - Discontinued
RCB; RCB0483
Cell line databases/resources DSMZCellDive; ACC-655
TOKU-E; 4118
Encyclopedic resources Wikidata; Q54901875
Gene expression databases GEO; GSM313802
GEO; GSM333797
GEO; GSM563355
GEO; GSM692872
GEO; GSM1366408
Polymorphism and mutation databases Cosmic; 1526627
Cosmic; 2131578
Cosmic; 2239461
Cosmic; 2301574
Cosmic; 2393635
Cosmic; 2485946
IARC_TP53; 21458
Progenetix; CVCL_1827
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number36