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Cellosaurus GK1.5 (CVCL_4523)

[Text version]
Cell line name GK1.5
Synonyms GK 1.5; GK-1.5
Accession CVCL_4523
Resource Identification Initiative To cite this cell line use: GK1.5 (RRID:CVCL_4523)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Monoclonal antibody isotype: IgG2b.
Monoclonal antibody target: UniProtKB; P06332; Mouse Cd4.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=6195085; DOI=10.1111/j.1600-065X.1983.tb01083.x
Deno Pete Dialynas, David B. Wilde, Philippa Marrack, Anne Pierres, Katherine A. Wall, Wendy Lynn Havran, Gillis R. Otten, Michael R. Loken, Michel Pierres, John Wayne Kappler, Frank Wesley Fitch;
Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity.
Immunol. Rev. 74:29-56(1983)

PubMed=6195255; DOI=10.4049/jimmunol.131.5.2178
David B. Wilde, Philippa Marrack, John Wayne Kappler, Deno Pete Dialynas, Frank Wesley Fitch;
Evidence implicating L3T4 in class II MHC antigen reactivity monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines.
J. Immunol. 131:2178-2183(1983)

Cross-references
Cell line collections (Providers) ATCC; TIB-207
BCRC; 60472
BCRJ; 0092
IZSLER; BS Hy 25
KCLB; 40207
Cell line databases/resources CLO; CLO_0003498
CLDB; cl5190
Encyclopedic resources Wikidata; Q54835871
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number13