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Cellosaurus 4MBr-5 (CVCL_4492)

[Text version]
Cell line name 4MBr-5
Synonyms 4MBR-5
Accession CVCL_4492
Resource Identification Initiative To cite this cell line use: 4MBr-5 (RRID:CVCL_4492)
Comments Group: Non-human primate cell line.
Characteristics: EGF dependent.
Senescence: Senesces at 40 PDL (PubMed=7065527).
Virology: Susceptible to infection by poliovirus type 1, type 2 and type 3 (PubMed=28046048).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Macaca mulatta (Rhesus macaque) (NCBI Taxonomy: 9544)
Sex of cell Female
Age at sampling 2-3Y
Category Finite cell line
Publications

CLPUB00288
Jane L. Caputo, Robert J. Hay, Carolyn D. Williams;
The isolation and properties of an epithelial cell strain from rhesus monkey bronchus.
In Vitro 15:222-223(1979)

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Robert J. Hay, Carolyn D. Williams, Marvin L. Macy, Kantharajapura Subbegowda Lavappa;
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

DOI=10.1007/978-94-011-3550-4_4
Robert J. Hay;
Development, availability and characterization of ATCC human and animal cell lines.
(In book chapter) Animal cell culture and production of biologicals; Sasaki, Ryuzo & Ikura, Koji (eds.); pp.27-39; Springer; Dordrecht; Netherlands (1991)

DOI=10.1016/B978-012361946-4/50009-0
Robert J. Hay;
Animal cells in culture.
(In book chapter) Maintaining cultures for biotechnology and industry; Hunter-Cevera, Jennie Charlotte & Belt, Angela (eds.); pp.161-187; Academic Press; San Diego; USA (1996)

PubMed=28046048; DOI=10.1371/journal.pone.0169391; PMCID=PMC5207746
Silvia Dotti, Tina Lombardo, Riccardo Villa, Andrea Cacciamali, Cinzia Zanotti, Nadia Andrea Andreani, Stefano Cinotti, Maura Ferrari;
Transformation and tumorigenicity testing of simian cell lines and evaluation of poliovirus replication.
PLoS ONE 12:e0169391.1-e0169391.13(2017)

Cross-references
Cell line collections (Providers) ATCC; CCL-208
IZSLER; BS CL 222
Cell line databases/resources CLO; CLO_0001400
Encyclopedic resources Wikidata; Q54603515
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17