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Cellosaurus TE-2 (CVCL_4455)

[Text version]
Cell line name TE-2
Synonyms TE2
Accession CVCL_4455
Resource Identification Initiative To cite this cell line use: TE-2 (RRID:CVCL_4455)
Comments Problematic cell line: Contaminated. TE-2, TE-3, TE-7, TE-12 and TE-13 have been shown to be identical (PubMed=17804709; PubMed=20143388). TE-2 was originally thought to originate from the primary tumor of the intrathoracic esophagus of a 57 year old Japanese male.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00275.
Population: Japanese.
Doubling time: 72 hours (PubMed=520749).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9971 ! TE-3
CVCL_9972 ! TE-7
CVCL_1762 ! TE-12
CVCL_4463 ! TE-13
Sex of cell Male
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=520749; DOI=10.20772/cancersci1959.70.5_575
Tetsuro Nishihira, Morio Kasai, Shozo Mori, Toshio Watanabe, Yoshiki Kuriya, Makoto Suda, Michihiko Kitamura, Katsu Hirayama, Takashi Akaishi, Takashi Sasaki;
Characteristics of two cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus.
Gann 70:575-584(1979)

PubMed=2990217; PMCID=PMC1888002
Carole Yee, Indira Krishnan-Hewlett, Carl C. Baker, Richard Schlegel, Peter Maxwell Howley;
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am. J. Pathol. 119:361-366(1985)

PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X
Susan P. Banks-Schlegel, Jesse Quintero;
Human esophageal carcinoma cells have fewer, but higher affinity epidermal growth factor receptors.
J. Biol. Chem. 261:4359-4362(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j
Jacqueline Whang-Peng, Susan P. Banks-Schlegel, Elaine C. Lee;
Cytogenetic studies of esophageal carcinoma cell lines.
Cancer Genet. Cytogenet. 45:101-120(1990)

PubMed=1778766; DOI=10.1111/j.1349-7006.1991.tb01816.x; PMCID=PMC5918361
Eisuke Takeshima, Michinari Hamaguchi, Tadashi Watanabe, Seiji Akiyama, Masato Kataoka, Yukano Ohnishi, Heng-Yi Xiao, Yoshiyuki Nagai, Hiroshi Takagi;
Aberrant elevation of tyrosine-specific phosphorylation in human gastric cancer cells.
Jpn. J. Cancer Res. 82:1428-1435(1991)

PubMed=8509434; DOI=10.1007/BF01215923
Tetsuro Nishihira, Yu Hashimoto, Masafumi Katayama, Shozo Mori, Toshio Kuroki;
Molecular and cellular features of esophageal cancer cells.
J. Cancer Res. Clin. Oncol. 119:441-449(1993)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172
Itaru Sonoda, Issei Imoto, Jun Inoue, Tatsuhiro Shibata, Yutaka Shimada, Koei Chin, Masayuki Imamura, Teruo Amagasa, Joe W. Gray, Setsuo Hirohashi, Johji Inazawa;
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer Res. 64:3741-3747(2004)

PubMed=17804709; DOI=10.1158/0008-5472.CAN-07-2064
Jurjen J. Boonstra, Albertina W. van der Velden, Erwin C.W. Beerens, Ronald van Marion, Yuiko Morita-Fujimura, Yasuhisa Matsui, Tetsuro Nishihira, Chris Tselepis, Pierre Hainaut, Anson W. Lowe, H. Berna Beverloo ...Show all 14 authors... , Herman van Dekken, Hugo W. Tilanus, Winand N.M. Dinjens; Show fewer authors
Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7.
Cancer Res. 67:7996-8001(2007)

PubMed=18973137; DOI=10.1002/gcc.20626
Takashi Sugimoto, Naohiko Seki, Satoya Shimizu, Naoko Kikkawa, Jun Tsukada, Hideaki Shimada, Keita Sasaki, Toyoyuki Hanazawa, Yoshitaka Okamoto, Akira Hata;
The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.
Genes Chromosomes Cancer 48:132-142(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) RCB; RCB1948 - Discontinued
TKG; TKG 0253 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4455
Cell_Model_Passport; SIDM00022
CGH-DB; 306-1
CGH-DB; 9255-4
Anatomy/cell type resources BTO; BTO_0002866
Biological sample resources BioSample; SAMN03151965
Chemistry resources ChEMBL-Cells; CHEMBL3307467
ChEMBL-Targets; CHEMBL615011
PubChem_Cell_line; CVCL_4455
Encyclopedic resources Wikidata; Q54972015
Gene expression databases GEO; GSM301572
Polymorphism and mutation databases Cosmic; 730307
Cosmic; 735782
Cosmic; 801323
Cosmic; 923174
Cosmic; 926098
Cosmic; 947595
Cosmic; 983714
Cosmic; 1123319
Cosmic; 1612897
Cosmic; 2650637
Cosmic; 2698419
Progenetix; CVCL_4455
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number30