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Cellosaurus TE-2 (CVCL_4455)

[Text version]
Cell line name TE-2
Synonyms TE2
Accession CVCL_4455
Resource Identification Initiative To cite this cell line use: TE-2 (RRID:CVCL_4455)
Comments Problematic cell line: Contaminated. TE-2, TE-3, TE-7, TE-12 and TE-13 have been shown to be identical (PubMed=17804709; PubMed=20143388). TE-2 was originally thought to originate from the primary tumor of the intrathoracic esophagus of a 57 year old Japanese male.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00275.
Population: Japanese.
Doubling time: 72 hours (PubMed=520749).
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9971 ! TE-3
CVCL_9972 ! TE-7
CVCL_1762 ! TE-12
CVCL_4463 ! TE-13
Sex of cell Male
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

PubMed=520749; DOI=10.20772/cancersci1959.70.5_575
Nishihira T., Kasai M., Mori S., Watanabe T., Kuriya Y., Suda M., Kitamura M., Hirayama K., Akaishi T., Sasaki T.
Characteristics of two cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus.
Gann 70:575-584(1979)

Yee C., Krishnan-Hewlett I., Baker C.C., Schlegel R., Howley P.M.
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am. J. Pathol. 119:361-366(1985)

PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X
Banks-Schlegel S.P., Quintero J.
Human esophageal carcinoma cells have fewer, but higher affinity epidermal growth factor receptors.
J. Biol. Chem. 261:4359-4362(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j
Whang-Peng J., Banks-Schlegel S.P., Lee E.C.
Cytogenetic studies of esophageal carcinoma cell lines.
Cancer Genet. Cytogenet. 45:101-120(1990)

PubMed=1778766; DOI=10.1111/j.1349-7006.1991.tb01816.x
Takeshima E., Hamaguchi M., Watanabe T., Akiyama S., Kataoka M., Ohnishi Y., Xiao H.-Y., Nagai Y., Takagi H.
Aberrant elevation of tyrosine-specific phosphorylation in human gastric cancer cells.
Jpn. J. Cancer Res. 82:1428-1435(1991)

PubMed=8509434; DOI=10.1007/BF01215923
Nishihira T., Hashimoto Y., Katayama M., Mori S., Kuroki T.
Molecular and cellular features of esophageal cancer cells.
J. Cancer Res. Clin. Oncol. 119:441-449(1993)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172
Sonoda I., Imoto I., Inoue J., Shibata T., Shimada Y., Chin K., Imamura M., Amagasa T., Gray J.W., Hirohashi S., Inazawa J.
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer Res. 64:3741-3747(2004)

PubMed=17804709; DOI=10.1158/0008-5472.CAN-07-2064
Boonstra J.J., van der Velden A.W., Beerens E.C.W., van Marion R., Morita-Fujimura Y., Matsui Y., Nishihira T., Tselepis C., Hainaut P., Lowe A.W., Beverloo H.B., van Dekken H., Tilanus H.W., Dinjens W.N.M.
Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7.
Cancer Res. 67:7996-8001(2007)

PubMed=18973137; DOI=10.1002/gcc.20626
Sugimoto T., Seki N., Shimizu S., Kikkawa N., Tsukada J., Shimada H., Sasaki K., Hanazawa T., Okamoto Y., Hata A.
The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.
Genes Chromosomes Cancer 48:132-142(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line collections (Providers) RCB; RCB1948 - Discontinued
TKG; TKG 0253 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4455
Cell_Model_Passport; SIDM00022
CGH-DB; 306-1
CGH-DB; 9255-4
Anatomy/cell type resources BTO; BTO:0002866
Biological sample resources BioSample; SAMN03151965
Chemistry resources ChEMBL-Cells; CHEMBL3307467
ChEMBL-Targets; CHEMBL615011
PubChem_Cell_line; CVCL_4455
Encyclopedic resources Wikidata; Q54972015
Gene expression databases GEO; GSM301572
Polymorphism and mutation databases Cosmic; 730307
Cosmic; 735782
Cosmic; 801323
Cosmic; 923174
Cosmic; 926098
Cosmic; 947595
Cosmic; 983714
Cosmic; 1123319
Cosmic; 1612897
Cosmic; 2650637
Cosmic; 2698419
Progenetix; CVCL_4455
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number28