Cellosaurus cell line MM537 (CVCL

Cellosaurus MM537 (CVCL_4451)

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Cell line name

MM537

Synonyms

MM 537

Accession

CVCL_4451

Resource Identification Initiative

To cite this cell line use: MM537 (RRID:CVCL_4451)

Comments

Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=17363583).
Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15048078; PubMed=17363583).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

Age unspecified

Category

Cancer cell line

STR profile

Source(s): CBA=CBA-1356

Markers:

Amelogenin	X
CSF1PO	11,12
D2S1338	18,24
D3S1358	14,15
D5S818	11,12
D7S820	12
D8S1179	12
D13S317	12
D16S539	11,12
D18S51	12
D19S433	12,14
D21S11	28,32.2
FGA	20,24
TH01	6
TPOX	8,10
vWA	14,16

Publications

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Sandra Pavey, Peter Johansson, Leisl Packer, Jennifer Taylor, Mitchell S. Stark, Pamela M. Pollock, Graeme J. Walker, Glen M. Boyle, Ursula Harper, Sarah-Jane Cozzi, Katherine Hansen ...Show all 20 authors... , Laura Yudt, Chris Schmidt, Peter Hersey, Kay Adrian Oswald Ellem, Michael G.E. O'Rourke, Peter G. Parsons, Paul S. Meltzer, Markus Ringner, Nicholas K. Hayward; Show fewer authors
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Mitchell S. Stark, Nicholas K. Hayward;
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Peter Johansson, Sandra Pavey, Nicholas K. Hayward;
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

Cross-references

Cell line collections (Providers)

CBA; CBA-1356
ECACC; 12070509

Cell line databases/resources

cancercelllines; CVCL_4451

Biological sample resources

BioSample; SAMN07624434

Encyclopedic resources

Wikidata; Q54906163

Gene expression databases

GEO; GSM162937
GEO; GSM226726

Polymorphism and mutation databases

Cosmic; 889029
Progenetix; CVCL_4451

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number