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Cellosaurus MCC6 (CVCL_4445)

[Text version]
Cell line name MCC6
Synonyms MCC6TC; MCC6 TC
Accession CVCL_4445
Resource Identification Initiative To cite this cell line use: MCC6 (RRID:CVCL_4445)
Comments Doubling time: 10.5 days (PubMed=8244578).
Caution: Was briefly displayed in Cell Bank Australia under catalog number CBA-1334 but was never distributed.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
Publications

PubMed=8244578; DOI=10.1002/ijc.2910550519
Joan Helen Leonard, John R. Bell, John Henry Kearsley;
Characterization of cell lines established from Merkel-cell ('small-cell') carcinoma of the skin.
Int. J. Cancer 55:803-810(1993)

PubMed=8026890; DOI=10.1002/ijc.2910580223
J. Angus F. Thomson, Joan Helen Leonard, K. McGregor, Richard A. Sturm, Peter G. Parsons;
A nonconsensus octamer-recognition sequence (TAATGARAT-motif) identifies a novel DNA binding protein in human Merkel cell carcinoma cell lines.
Int. J. Cancer 58:285-290(1994)

PubMed=11433400; DOI=10.1002/ijc.1352
Anthony L. Cook, Pamela M. Pollock, John Welch, Michael D. Walsh, Rayleen V. Bowman, Kathryn C. Baumann, Nicholas K. Hayward, Joan Helen Leonard;
CDKN2A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine (Merkel cell) carcinoma of the skin.
Int. J. Cancer 93:361-367(2001)

PubMed=12209986; DOI=10.1002/ijc.10554
Joan Helen Leonard, Anthony L. Cook, Mireille Van Gele, Glen M. Boyle, Kelly J. Inglis, Frank Speleman, Richard A. Sturm;
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.
Int. J. Cancer 101:103-110(2002)

Cross-references
Cell line collections (Providers) ECACC; 21102105
Encyclopedic resources Wikidata; Q54904261
Polymorphism and mutation databases Cosmic; 912928
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number12