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Cellosaurus LIM2550 (CVCL_4442)

[Text version]
Cell line name LIM2550
Synonyms LIM 2550; LIM-2550
Accession CVCL_4442
Resource Identification Initiative To cite this cell line use: LIM2550 (RRID:CVCL_4442)
Comments From: Ludwig Institute for Cancer Research, Melbourne Branch; Melbourne; Australia.
Microsatellite instability: Instable (MSI) (PubMed=19378335; PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): CBA=CBA-0169; PubMed=25926053

Markers:
AmelogeninX,Y
CSF1PO12
D2S133817,23
D3S135815,18
D5S81812,13
D7S8209,10
D8S117914,15
D13S31712,15
D16S5399,14
D18S5113,14
D19S43311,14
D21S1129,31.2
FGA21,22
TH018,9
TPOX8
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=19378335; DOI=10.1002/ijc.24289
Hui-Hua Zhang, Francesca E. Walker, Sara Kiflemariam, Robert H. Whitehead, David Williams, Wayne A. Phillips, Thomas Mikeska, Alexander Dobrovic, Antony Wilks Burgess;
Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Int. J. Cancer 125:297-307(2009)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) CBA; CBA-0169
ECACC; 12070504
Cell line databases/resources cancercelllines; CVCL_4442
ColonAtlas; LIM2550
Biological sample resources BioSample; SAMN07624417
Encyclopedic resources Wikidata; Q54902540
Gene expression databases GEO; GSM1448168
Polymorphism and mutation databases Cosmic; 1238058
Cosmic; 1486140
Cosmic; 1805262
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28